DOWNLOAD | Autoimmune-Regulating Pathways


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While a healthy immune system functions to protect the body against disease and foreign pathogens, autoimmune diseases occur when the immune system malfunctions and immune cells mistakenly attack healthy cells and tissues.

The causes of autoimmune diseases, such as Rheumatoid Arthritis, Multiple Sclerosis, Lupus, Inflammatory Bowel Diseases, Type 1 Diabetes, are largely unknown and there is a clear need to elucidate mechanisms driving disease progression. Strategies to modulate the immune system have shown promise for controlling disease progression and reducing inflammation. Several signaling pathways involved in regulating the immune system are of interest for their therapeutic potential.

Download this bundle of curated pathways and diagrams to learn more about the following immune-regulating pathways and facilitate your autoimmune disease research.

  • NF-kB
  • Inflammasome
  • T Cell Signaling
  • B Cell Signaling
  • Jak/STAT
  • Fibrosis
  • Apoptosis
  • Cell Intrinsic Innate Immunity
  • Autophagy
  • Immune Cell Marker Guides (mouse only IHC and Flow)