Fluorescent Multiplex Immunohistochemistry Resources

Our extensive validation and advanced technical support ensures that all of our IHC-P-validated antibodies can be used for fluorsecent multiplex IHC. Learn More >
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mIHC T Cell Tech Note

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Characterize Immune Checkpoint Proteins and
T Cell Exhaustion Using Multiplex IHC

Advantages of multiplexing with our validated antibodies against targets relevant in cancer and immuno-oncology:
Immune checkpoint proteins and T cell exhaustion markers. Examples of mIHC data obtained in FFPE ovarian carcinoma and NSCLC samples. Protocol optimization steps for multiplexing with six targets.
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Multiplex IHC Detection of Immune Checkpoint Receptors in the Tumor Microenvironment (Poster)


 

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Characterize myeloid cell mediated immunosuppression in the tumor microenvironment using multiplex IHC

This application note focuses on how examining suppressive myeloid cells and other markers of the TME is made possible by multiplexing with IHC-validated antibodies.

 

Tumor Microenvironment Poster
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Tumor Immunology: examining the microenvironment

This poster features a complex interplay of the various cellular components of the tumor microenvironment, with particular emphasis on tumor infiltrating lymphocytes and mechanisms of immune suppression. (mailing address required to get free print poster)

Tyramide-based fluorescent mIHC Tech Note
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Fluorescent Multiplex Immunohistochemistry with Tyramide Signal Amplification

This application note focuses on protocol considerations for signal amplification in mIHC to detect PD-L1, VISTA, B7-H4, CD8α, and Cytokeratin. 

2017 Tricon Poster mihc immunotherapy
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Highly Multiplexed IHC Assays to Examine Immune Checkpoints and Biomarkers for Immunotherapy (Poster)

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Characteristics of Immune Infiltrate and Checkpoint Protein Expression Patterns in Murine Sygeneic Tumors via Multiplex Immunohistochemistry (Poster)

Mouse Syngeneic Models App Note
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Visualize Immune Infiltrate and Checkpoint Proteins in Murine Syngeneic Models (Application Note)