Explore Immuno-Oncology with These Pathway Diagrams

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Immune Checkpoint Signaling

Immune checkpoints refer to the inbuilt control mechanisms of the immune system that maintain self-tolerance and help to avoid collateral damage during a physiological immune response.

 

Conjugates for Flow Cytometric Analysis of Immune Cell Signaling
 

Investigate immune checkpoints like PD-L1, PD-1, TIM-3, Galectin-9, and CD40L/CD40 with conjugates validated for flow cytometry.

 

T Cell Receptor Signaling

T Cell Receptor (TCR) activation promotes a number of signaling cascades that ultimately determine cell fate through regulating cytokine production, cell survival, proliferation, and differentiation.


Conjugates for Flow Cytometric Analysis of T Cell Receptor Signaling

Investigate T Cell Receptor Signaling with flow cytometry, a strong technique for analyzing immune cells in a heterogenous population. Find conjugates relevant to T Cell Signaling and validated for use by flow cytometry.

 

CAR Signaling Networks

CAR-T cells act as a “living drug” that identify and kill cells expressing this marker by harnessing the cytotoxic abilities of T cells.

 

Tumor-Infiltrating Immune Cell Marker Guide for IHC (Human)

This guide reveals important functional state and cell markers for tumor-infiltrating immune cells in humans, optimized for immunohistochemistry.

 

Tumor-Infiltrating Immune Cell Marker Guide for IHC (Mouse)

This guide highlights the key functional state and cell markers for tumor-infiltrating immune cells in mice, like CD86 and Ly-6G, optimized for immunohistochemistry.

 

Tumor-Infiltrating Immune Cell Marker Guide for Flow Cytometry (Human)

This guide elucidates the network of different immune cell varieties and functional states in the tumor microenvironment in humans, optimized for flow cytometry.

 

Tumor-Infiltrating Immune Cell Marker Guide for Flow Cytometry (Mouse)

This guide reveals the network of different immune cell varieties and functional states in the tumor microenvironment in mice, optimized for flow cytometry.