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In neurodegenerative disease, the progressive loss of neuronal structure and function ultimately affect a patient’s mobility, mental function, and emotional control. These effects may be caused by genetic mutations or protein folding disorders that accumulate with age. Although the pathophysiologies of amyloid plaques and neurofibrillary tangles are well studied, the cellular processes that drive neurodegeneration are still not fully understood. Different neurodegenerative diseases share key cellular processes, so therapeutic efforts targeting one pathway may be applicable for the progression of many conditions.
Download this bundle of pathways and diagrams today for a better understanding of the fundamental mechanisms involved in neurodegeneration. Gain knowledge that can help support the development of therapeutics for diseases such as Alzheimer’s Disease, Parkinson’s Disease, multiple sclerosis, amyotrophic lateral sclerosis, and Huntington’s Disease.
- Parkinson's Disease Pathway Poster
- Alzheimer's Disease Signaling
- TREM2 Signaling
- Vesicle Trafficking/Presynaptic Signaling
- Post-Synaptic Signaling
- Neuronal and Glial Cell Marker Atlas
- Biomolecular Condensate Markers